Andy Murray is the world number four and can match any of the above trio on grass or hard court, although clay is another matter and the Brit is carrying an injury which might mean an early exit at Roland Garros.
It is hard to see past Nadal for many punters, whose dominance of the French Open has been virtually complete in the past few years, with the Spaniard having claimed six titles in the past seven years.
2009 was the only year in which Rafa failed to win this Grand Slam, losing to Robin Soderling and he warmed up in style by beating Djokovic in the Rome final, with the bookies offering a best price 4/6 (Betfred free bets) that Nadal claims a seventh crown.
Djokovic is the number one seed and did spend much of 2011 beating Nadal on clay although the Serbian failed to produce the goods when it mattered and the bookies aren’t convinced that the world number one can claim his first title at Roland Garros.
Novak has the added complication of a potential semi-final against Federer and that is why you can get odds of 11/4 (Betfred) that the Australian Open champion claims a sixth Grand Slam title.
As for Federer, this legend of tennis shows little sign of slowing down, although it’s clear that the 30-year-old can’t improve any further and the Swiss already has a French Open title under his belt.
It has been over two years since Federer won a Grand Slam event, although odds of 10/1 are available that he wins in Paris and the world number three comes into this tournament enjoying some decent form, despite clay never being his best surface.
Murray is as big as 40/1 to win the French, while David Ferrer is probably a better bet at the same odds with Paddy Power considering that the number six seed is always a tough customer on clay and should have a better record than just two quarter final appearances in this tournament.
Juan Martin del Potro is the other player that can cause damage in this Grand Slam, with the Argentine entering as the number nine seed and his quarter final appearance in the Australian Open a few months ago illustrated that he is capable of playing very well in the big tournaments.