Victory against Leeds United would put Chelsea into the semi-finals of the competition and the fact that Aston Villa, Swansea City and Bradford City are the other teams in the final four means that the London side would be strong favourites to lift this piece of silverware.
Benitez’s men have just returned from Japan where they were unsuccessful in their bid to win the Club World Cup after losing to Corinthians in the final and the Spaniard must now decide which players to rest ahead of the weekend and which ones can do a job against determined Championship opponents.
The bookies go odds-on about Chelsea although you can get 5/6 (William Hill free bets) about an away win in ninety minutes which might seem like a big price if Juan Mata, Oscar, Eden Hazard and Fernando Torres are on the pitch.
Oscar was reportedly unhappy to be left out of the team that eventually lost to Corinthians last week although he might get the chance to take out his frustration on Leeds and can be backed at 10/1 (bet365 £200 free bets) to score the first goal of the game.
That man Torres is a 9/2 chance (BetVictor bookmaker) although it might be that Daniel Sturridge instead gets a chance to impress the manager, with odds of 7/1 about the Chelsea striker looking a decent price if he gets a starting role instead of his team-mate.
As for Leeds United, they will be hoping to delight their fanatical supporters by winning this clash and odds of 7/2 (Blue Square £25 free bet) could turn out to be a gift considering the second-flight team have had lots of preparation time for this encounter.
They also come into this match in decent form considering they have won their last three matches at Elland Road, with Ross McCormack now chomping at the bit to get involved following his return from injury, while El Hadji Diouf seems to raise his game for big encounters and played a starring role when United beat Everton in an earlier round.
It would be no surprise if this match went to extra-time and perhaps Leeds will draw inspiration from Yorkshire counterparts Bradford City who managed to take Arsenal to penalties before dumping the Gunners out of the competition.