The Red Devils have won at Eastlands already this term, claiming a dramatic 3-2 win in the FA Cup back in January which saw Vincent Kompany sent off, United take a 3-0 lead only for City to come right back into the match and nearly force a replay.
You could argue that Sir Alex Ferguson has the more experienced players for this kind of occasion, with Paul Scholes, Ryan Giggs, Patrice Evra and Rio Ferdinand all well versed when it comes to crunch matches that have a bearing on league titles.
Those looking to back United can get handsome odds of 5/2 (Bet Victor free £50 bet) that the visitors seal the Premier League title in their arch-rivals’ back yard, although we should note that a point would keep the champions firmly in the driving seat.
You can get odds of 5/2 (bet365 bookmaker) that the game ends all square, with Ferguson determined to avoid a repeat of the humiliation suffered at Old Trafford where City ran riot to win 6-1 back in autumn. At that stage, it appeared as though Roberto Mancini’s side were champions-elect.
However, Manchester City have since lost their way, especially on the road where David Silva’s loss of form has seen the goals dry up and they simply need to win this match to keep alive their hopes of becoming champions.
Odds of 5/4 (Paddy Power free bets) are available about the blue half of Manchester celebrating on Monday night and let’s not forget that City have slipped up just once at home in the Premier League this term, recently drawing 3-3 with Sunderland.
Mario Balotelli opened the scoring at Old Trafford in the reverse fixture and the Italian could make a surprise start in this contest, despite several misdemeanours which has caused Mancini to state that the player would probably be sold in the summer.
Even so, one would imagine that it will be Carlos Tevez lining up against his former club and the Argentine is a 7/1 chance (Stan James) to score first, with Sergio Aguero also the same price with the same firm to break the deadlock.
United would be feeling a good deal more comfortable about winning the Premier League if they hadn’t conceded two late goals to Everton to draw 4-4 last weekend, although there is little doubting that Wayne Rooney is in sparkling form and he is a 7/1 chance to send the Red Devils on their way to victory by scoring first.