Didier Deschamps’ side finished second behind Arsenal in qualifying and ahead of Olympiacos and Borussia Dortmund in what was a competitive heat, although the French side did lose two of their three group matches at the Stade Vélodrome.
They can’t afford for the same thing to happen on Wednesday night and are strong favourites at 5/4 (Paddy Power £100 free bets) to establish a first leg advantage against Claudio Ranieri’s team, something which could prove to be a popular bet.
Marseille have not lost any of their past 14 games but the same cannot be said of Internazionale, who have lost five of their last six matches and Ranieri might be out of a job should they be knocked out of the Champions League.
The visitors can be backed at 13/5 (Coral bookmaker) to claim a much-needed victory, although the only time they have avoided defeat recently was a remarkable 4-4 draw with Palermo where Diego Milito managed a four-timer.
The Argentine is a 13/2 chance to score first in this match, although Loic Remy could fancy his chances of finding the net against a porous defence and he is an 11/2 poke.