Meanwhile, Arsenal have enjoyed a strong start to the season and will travel north to the Etihad Stadium hoping to continue their defensively mean ways, with Manchester City licking their wounds after that dramatic defeat at the Bernabeu Stadium.
The third game on Sunday will see Tottenham attempt to build on their 3-1 win at Reading when they host QPR in a London derby which will see Bobby Zamora return to his old club.
Liverpool v Manchester United 13:30
We can practically disregard the performance and scoreline from Thursday’s Europa League match against Young Boys with Brendan Rodgers admitting that the Premier League ranks as a much bigger priority at this point of the season and the best players will be rested for Sunday’s north-west derby.
Liverpool have had a tough start to the season which has seen them draw two and lose two, although they played well enough to beat Manchester City at Anfield, while last week’s 1-1 draw at Sunderland was deserved and saw them play pretty well.
The Merseyside outfit are 15/8 (Betfred free bets) to claim their first league victory of the season, with a similar team to be named from the side that started at the Stadium of Light and that means Fabio Borini and Raheem Sterling flanking Luis Suarez.
Suarez will be roundly booed by the opposition fans after his clash with Patrice Evra at Anfield last season although the Uruguayan has begun the season brightly and can be backed at 15/2 to score the first goal of this game.
Manchester United are slight favourites to claim a maximum haul and bet365 offer 13/8 about Sir Alex Ferguson’s team winning their fourth Premier League in a row, although they weren’t convincing when beating Galatasaray on Wednesday night.
Robin van Persie will start in attack for the visitors and is a best price 6/1 to score the first goal of the game, while Wayne Rooney is fighting to play some part in the match and can be backed at 7/1.
It’s easy to see the teams cancelling each other out and a draw is on offer at 12/5, with Under 2.5 Goals looking like a decent shout at 17/20.
Manchester City v Arsenal 16:00
Games between these two teams are always incident-packed and we should expect a few fireworks on Sunday afternoon as Manchester City look to bounce back from that 3-2 defeat to Real Madrid by beating one of their Premier League title rivals.
The champions twice led in the Bernabeu before the late late show from Real and Roberto Mancini will now be focusing his players on maintaining their 100% record at the Etihad Stadium and keeping pace with Chelsea at the top of the table.
City are a best price 4/5 (BetVictor) to claim the points just as they did in this fixture last season, with Sergio Aguero having now recovered from injury to potentially play a part against the Gunners. Carlos Tevez is likely to start and can be backed at 5/1 to break the deadlock although the Arsenal defence haven’t looked this stubborn for a long time.
Steve Bould seems to have made a real difference as defence coach and just one goal has been conceded in four games to date, with the north London side having won recent matches against Liverpool and Southampton to forge their way into the top four.
Paddy Power offer 4/1 that the visitors are celebrating come the final whistle and they have so many attacking options despite the sale of Robin van Persie to Manchester United. Arsene Wenger seems to have crafted Gervinho into a striker, Lukas Podolski has a couple of goals to his name already and Olivier Giroud will eventually find his feet.
Then there’s the impressive Santi Cazorla pulling the strings in midfield and the Spaniard is as big as 14/1 to open the scoring, although there’s a school of thought which suggests that this will be a low-scoring affair and a 1-0 win in City’s favour is 8/1.
Tottenham v QPR 16:00
Plenty of people backed Tottenham to beat West Brom and Norwich at home, although the Baggies and Canaries got themselves deserved equalisers at White Hart Lane to leave punters frustrated.
Perhaps Spurs will break their home duck in this London derby and William Hill offer a best price 1/2 about this happening, although Andre Villas-Boas named a strong team against Lazio in the Europa League and a lot depends on whether the players have recovered in time.
Jermain Defoe should have had a hat-trick at Reading when his team won 3-1 and the striker will be looking to bolster his tally, with the bookies going a best price 4/1 about the player scoring first against a QPR side that held Chelsea to a goalless draw last weekend.
Rangers are yet to win a match this season although they have played Chelsea and Manchester City, while the defence seems to be a lot more solid compared to that opening day 5-0 drubbing at the hands of Swansea on the first day of the season.
QPR are a 13/2 chance to win at White Hart Lane and manager Mark Hughes will certainly consider this to be a good time to play this fixture considering Spurs are looking to win the Europa League despite this potentially damaging their domestic form.