While the Brit has had several near-misses when it comes to claiming a Grand Slam title, the fact that he reached the Wimbledon final before claiming Olympic gold in SW19 suggests that the time is now ripe for the 25-year-old to start writing his legacy.
It has been four years since Murray reached the final at Flushing Meadows, an occasion which was the first of his four runner-up slots in major tournaments, although the Scot has to be the value bet at 4/1 (Boylesports) considering he beat Federer and Djokovic in the Olympic tournament.
Murray has been drawn in the same half as first seed Roger Federer, something that means he might have to beat the Swiss and Novak Djokovic to go all the way, although the Serbian’s form hasn’t been on a par with 2011 and might be vulnerable in the early stages.
Even so, the bookies make the reigning champion the player to beat and Rafael Nadal’s absence means that the 25-year-old could be spared a potentially titanic semi-final against the Spaniard, with a best price of 11/8 (bet365 £200 free bets) on offer about the world number two.
As for Federer, who can quibble with the 31-year-old’s status as the greatest player ever to pick up a racquet, especially after the Swiss ended an two-and-a-half year Grand Slam drought by winning the 2012 Wimbledon title.
The 17-time Grand Slam winner is a best price 11/4 to claim the spoils with Boylesports, who are clearly intent on keeping Djokovic on side for this tournament.
Naturally, at least one other player will make the semi-finals so we can’t completely narrow down the field to three, especially as surprise results do happen. Juan Martin Del Potro knows what’s required to win on the hard courts at Queen’s and he is a best price 16/1 (Sportingbet) to claim his second US Open title.
Jo-Wilfried Tsonga is always a dangerous opponent whose big serve is suited to this surface and David Ferrer is also capable of playing at the level required to win a major, although it counts against the Spaniard that he’s never reached a Grand Slam final.
Several bookmakers such as bet365 are offering live streaming from the show courts of the US Open, something which will be a treat for customers, while there are also some great money back offers including Blue Square refunding outright bets if Andy Murray wins.