Defeat at the DW Stadium would see Wigan close the gap to seven points with 11 games remaining and you have the added factor of Roberto Martinez being the former manager of the Swans who effectively laid the foundations for the future success of the Welsh club.
Martinez left the Liberty Stadium when Athletic came calling and the Spaniard has successfully kept Wigan in the Premier League although he has a job on his hands this time around and the Latics have been rock bottom for much of the campaign.
The home side can be backed at 6/4 (William Hill free bets) to claim a precious three point haul and they did play reasonably well against Aston Villa last weekend even if it was the visitors who had the best chances as the teams played out a goalless draw.
Indeed, scoring goals has been a perennial problem for the basement boys, who have managed to find the net just 11 times in 13 home games. Swansea have been similarly shot-shy on the road with just ten goals in 13 matches and the Under 2.5 Goals quote stands out at odds of 8/11 (Sky Bet).
The two teams played out a goalless draw in south Wales earlier this term, with Swansea available at 21/10 (Bet Victor free bets) to win this match and they have collected a couple of victories on the road this term.
In Danny Graham, they have a forward who might have made all the difference for Wigan and the former Middlesbrough man is a 7/1 chance with Boylesports to break the deadlock.